Companies/US/ALNY

ALNYLAM PHARMACEUTICALS, INC.

Last · NasdaqGS$224.47+0.65 (+0.29%)close · yahoo · 18h ago
Vol 1.11M ≈ 248.11M
Market cap$30.04B133.8M sh
P/E · TTM37.9fwd 18.0 · eps 5.93
Beta0.27vs S&P 500
Div yield0.00%annual · TTM
52w range
$197.81$495.55
Volume1.1Msession

Issuer

Legal nameALNYLAM PHARMACEUTICALS, INC.
HQUnited States (US)
ListingUS ALNY
ISINUS02043Q1076
SectorHealthcare
IndustryDrugs (Pharmaceutical)
SIC2834
CurrencyUSD
Entity registrysec:0001178670
CIK0001178670
Employees2,500
AddressAlnylam Pharmaceuticals, Inc. 675 West Kendall Street 02142, Cambridge +617 551 8200
Headline financial metrics
Revenue$4.8B
Operating income$999.8M
Net income$808.0M
Free cash flow$793.9M
Operating margin20.8%
Net margin16.8%
Return on equity59.7%
PeriodTTM 2026-06-30
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OpenFilings analyst

Our analyst

10-K · 2026-02-12

From latest 10-K · 2026-02-12

  • Amvuttra Concentration
  • Rna Interference Pipeline
  • First Profitability
  • Sanofi Royalties
  • Customer Concentration
  • Attr Competition
  • Convertible Debt

Red flags

  • AMVUTTRA generated $2.31 billion, approximately 77% of 2025 net product revenue of $2.99 billion; the company explicitly states that future results depend on sustaining and growing AMVUTTRA sales.
  • Distributor A represented 45% of consolidated revenue in 2025, up from 29% in 2024, indicating substantial customer concentration.
  • Sanofi royalties on global AMVUTTRA sales range from 15% to 30%, with the top 30% tier applying to annual sales above $1.50 billion; this structurally limits gross-margin expansion.
  • The company still had an accumulated deficit of $6.70 billion despite 2025 net income of $314 million, and expects operating results to fluctuate materially.
  • The $661.3 million of 0.00% convertible notes due 2028 and other convertible debt create potential future cash settlement, refinancing or dilution exposure.

Upcoming earnings

1 event
1:30 PM UTC+1
Period
Sep 2026
Est. EPS
$2.27
Est. revenue
1.4B

Earnings transcripts

7 recent

Documents

FormReporting forFiledFlags
2026-10-022026-10-060
2026-09-192026-09-220