Companies/US/VRTX

VERTEX PHARMACEUTICALS INCORPORATED

Last · NASDAQ$498.50+13.28 (+2.74%)close · yahoo · 18h ago
Vol 2.09M ≈ 1.04B
Market cap$126.27B253.3M sh
P/E · TTM29.0fwd 24.8 · eps 17.17
Beta0.28vs S&P 500
Div yield0.00%annual · TTM
52w range
$403.16$560.25
Volume2.1Msession

Issuer

Legal nameVERTEX PHARMACEUTICALS INCORPORATED
HQUnited States (US)
ListingUS VRTX
ISINUS92532F1003
SectorHealthcare
IndustryDrugs (Pharmaceutical)
SIC2834
CurrencyUSD
Entity registrysec:0000875320
CIK0000875320
LinkedIn
Employees6,400
AddressVertex Pharmaceuticals, Inc. 50 Northern Avenue 02210, Boston +617 341 6100
Headline financial metrics
Revenue$12.6B
Operating income$4.8B
Net income$4.4B
Free cash flow$3.8B
Operating margin38.0%
Net margin35.0%
Return on equity21.8%
PeriodTTM 2026-06-30
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OpenFilings analyst

Our analyst

10-K · 2026-02-13

From latest 10-K · 2026-02-13

  • Cf Revenue Concentration
  • Journavx Launch
  • Casgevy Adoption
  • Pipeline Investment
  • Pricing Reimbursement
  • Gene Editing Manufacturing

Red flags

  • Substantially all net product revenue has historically come from CF medicines, creating concentration risk around manufacturing or supply disruption, safety findings, competition, and pricing pressure.
  • CASGEVY revenue was only $115.8 million in 2025 despite approval across multiple geographies; adoption remains constrained by complex manufacturing and administration requirements.
  • Total R&D and SG&A reached $5.7 billion in 2025, up from $5.1 billion, while 2026 development and commercial expenses are expected to increase further.
  • Pricing and reimbursement risk is concrete: TRIKAFTA was selected for a Colorado affordability review, and Vertex faces broader government and payer pressure on access and drug pricing.

Upcoming earnings

1 event
9:00 PM UTC+1
Period
Sep 2026
Est. EPS
$0.04
Est. revenue
3.4B

Earnings transcripts

1 recent

Documents

FormReporting forFiledFlags
2026-09-082026-09-100
2026-08-282026-09-010
2026-08-272026-08-310
2026-06-302026-08-040