SPERO THERAPEUTICS, INC.
Ownership & governance
Executives 3Directors 8Avg age 59Avg tenure 5.6y
ER
Esther Rajavelu
Chief Executive Officer
Age 47Since 2025-01-09Profile →
+10
Executives3
Board of directors8
MD
Milind Deshpande→
Chairman
Age 69Since 2013-12-31
PV
Patrick Volkert Vink→
Director/Board Member
Age 62Since 2015-08-31
FT
Frank Thomas→
Chairman
Age 56Since 2025-01-09
JP
John Pottage→
Director/Board Member
Age 73Since 2018-08-31
CS
Cynthia Smith→
Director/Board Member
Age 57Since 2019-03-18
SJ
Scott Jackson→
Director/Board Member
Age 61Since 2020-04-15
KT
Kathleen Tregoning→
Director/Board Member
Age 55Since 2021-10-10
ER
Esther Rajavelu→
Director/Board Member
Age 47Since 2025-06-11
Shareholders5
| Name | Stake | Shares |
|---|---|---|
| GSK PLC | 15.87 % | 9,190,606 |
| PFIZER INC. | 4.08 % | 2,362,348 |
| Vanguard Capital Management LLC | 3.109 % | 1,799,880 |
| Renaissance Technologies LLC | 2.054 % | 1,189,235 |
| Esther Rajavelu | 1.704 % | 986,851 |
Catalog · 2026-07-09
Registry officers11
| Name | Role | Since | Shares |
|---|---|---|---|
| Esther Rajavelu | Chief Executive Officer | 2025-01-09 | - |
| Frank Thomas | Chairman | 2025-01-09 | - |
| Milind Deshpande | Chairman | 2013-12-31 | - |
| Timothy Keutzer | Chief Operating Officer | 2023-01-31 | - |
| Cynthia Smith | Director/Board Member | 2019-03-18 | - |
| Esther Rajavelu | Director/Board Member | 2025-06-11 | - |
| John Pottage | Director/Board Member | 2018-08-31 | - |
| Kathleen Tregoning | Director/Board Member | 2021-10-10 | - |
Registry · as of 2026-07-09
Institutional (13F)
Loading Form 13F holders…
Fund membership
Loading fund baskets…
Street consensus
Consensus noneMean target 5Range 4–6Analysts 2
4Mean 56
- Buy 1
- Hold 1
Broker actions40 of 45
| Firm | Action | To | Target | Date |
|---|---|---|---|---|
| HC Wainwright & Co. | Maintained | Buy | 6 | 2026-09-14 |
| HC Wainwright & Co. | Reiterated | Buy | 5 | 2025-01-30 |
| Evercore ISI Group | Downgrade | In-Line | 5 | 2024-12-20 |
| HC Wainwright & Co. | Reiterated | Buy | 5 | 2024-12-02 |
| TD Cowen | Downgrade | Hold | — | 2024-11-18 |
| Cantor Fitzgerald | Reiterated | Overweight | — | 2024-11-15 |
| HC Wainwright & Co. | Maintained | Buy | 5 | 2024-11-04 |
| HC Wainwright & Co. | Reiterated | Buy | 7 | 2024-10-03 |
| TD Cowen | Upgrade | Buy | — | 2024-08-06 |
| Cantor Fitzgerald | Reiterated | Overweight | — | 2024-08-06 |
| HC Wainwright & Co. | Reiterated | Buy | 7 | 2024-08-06 |
| HC Wainwright & Co. | Reiterated | Buy | 7 | 2024-05-16 |
Firm rows and rating mix from Yahoo Finance; mean target is Yahoo’s aggregate until OpenFilings derives consensus from broker rows.