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Item 9.01. Financial Statements and Exhibits. (d) Exhibits. Exhibit Number Description 99.1 Investor Presentation. 104 Cover Page Interactive Data File (formatted as Inline XBRL and contained in Exhibit 101). Field: Page; Sequence: 2; Options: NewSection; Value: 2 Field: Sequence; Type: Arabic; Name: PageNo 2 Field: /Sequence Field: /Page SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized. ORCHESTRA BIOMED HOLDINGS, INC. By: /s/ Andrew Taylor Name: Andrew Taylor Title: Chief Financial Officer Date: September 8, 2026 Field: Page; Sequence: 3; Options: Last Field: Sequence; Type: Arabic; Name: PageNo 3 Field: /Sequence Field: /Page Field: Set; Name: xdx; ID: xdx_08B_extensions eJxFjV0KwjAQhE/QOyx5LtpGBe2blipiFSkivga7lWCbLZv4dyRvaWwRl4VlmflmhAjFipa6RobTosjhgE1bK4dQYIWM5ozeka43Cfhb4EVbx8q47v2BKXkGPTMZyJHyQme9a4tlAtF0GMuhHEM0S0YTmG9F8NVTMpUu0TitalCmhD1Tyxqd4lefcFBPMtS8uqojstVkEogHUS+/QUaxhB3d1YP4aiHPUxGE3QRixXRrvSt7OjRfErIaG19ne/q/wQcDIEqG