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Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers On July 19, 2026, Serina Therapeutics, Inc. (the “Company”), together with its subsidiary Serina Therapeutics (AL), Inc., entered into an Amended and Restated Employment Agreement (the “A&R Employment Agreement”) with Steve Ledger, the Company’s Chief Executive Officer. The A&R Employment Agreement amends and restates in its entirety the Employment Agreement among the parties dated September 9, 2024. Under the A&R Employment Agreement, Mr. Ledger will receive an annual base salary of $500,000 and will be eligible for a target annual bonus equal to 50% of his base salary based on the achievement of annual goals established by the Board of Directors. The A&R Employment Agreement also reflects Mr. Ledger’s previously granted stock options and provides that he remains eligible to receive additional equity awards in the discretion of the Board. If Mr. Ledger’s employment is terminated by the Company without Cause or he resigns for Good Reason (each as defined in the A&R Employment Agreement), other than in connection with a Change in Control (as defined in the A&R Employment Agreement), and subject to his execution and non-revocation of a release of claims, he will be entitled to (i) 12 months of his then-current base salary plus a pro-rated annual bonus based on his target annual bonus, payable in a lump sum within 60 days after termination, and (ii) reimbursement of COBRA premiums for up to 12 months. If Mr. Ledger experiences a qualifying termination in connection with a Change in Control (a termination by the Company without Cause or a resignation for Good Reason occurring during the period beginning three months before, and ending 12 months after, the consummation of a Change in Control), and subject to his execution and non-revocation of a release of claims, he will instead be entitled to (i) an amount equal to 1.5 times his then-current base salary, (ii) an amount equal to 1.5 times his target annual bonus, (iii) a pro-rated annual bonus based on his target annual bonus, in each case payable in a lump sum within 60 days after termination, (iv) reimbursement of COBRA premiums for up to 18 months, and (v) full accelerated vesting of his then-unvested time-based equity awards. The A&R Employment Agreement