Financial Statements (unaudited)
Item 1. Financial Statements. ORCHESTRA BIOMED HOLDINGS, INC. Condensed Consolidated Balance Sheets (in thousands, except share and per share data) (Unaudited) June 30, December 31, 2026 2025 ASSETS CURRENT ASSETS: Cash and cash equivalents $ 20,472 $ 34,690 Marketable securities 89,491 71,822 Accounts receivable, net 51 95 Inventory 250 310 Prepaid expenses and other current assets 977 994 Total current assets 111,241 107,911 Property and equipment, net 2,045 1,715 Right-of-use assets 1,171 1,496 Strategic investments — 2,495 Deposits and other assets 1,243 1,240 TOTAL ASSETS $ 115,700 $ 114,857 LIABILITIES, SERIES A PREFERRED STOCK AND STOCKHOLDERS’ EQUITY CURRENT LIABILITIES: Accounts payable $ 6,132 $ 6,095 Accrued expenses and other liabilities 6,531 9,890 Operating lease liability, current portion 808 751 Total current liabilities 13,471 16,736 Royalty purchase agreement 34,593 16,482 Note payable 20,442 — Loan payable 14,397 14,268 Derivative liability 2,460 2,749 Operating lease liability, less current portion 520 936 Other long-term liabilities 397 308 TOTAL LIABILITIES 86,280 51,479 Series A Preferred Stock, $ 0.0001 par value per share; 200,000 issued and outstanding at June 30, 2026 and December 31, 2025; aggregate liquidation preference of $ 20,000 10,097 9,808 STOCKHOLDERS’ EQUITY Preferred stock, $ 0.0001 par value, 10,000,000 shares authorized; — — Common stock, $ 0.0001 par value per share; 340,000,000 shares authorized; 60,105,049 and 57,032,963 shares issued and outstanding as of June 30, 2026 and December 31, 2025, respectively. 6 6 Additional paid-in capital 426,423 416,083 Accumulated other comprehensive (loss) income ( 81 ) 60 Accumulated deficit ( 407,025 ) ( 362,579 ) TOTAL STOCKHOLDERS’ EQUITY 19,323 53,570 TOTAL LIABILITIES, SERIES A PREFERRED STOCK AND STOCKHOLDERS’ EQUITY $ 115,700 $ 114,857 The accompanying notes are an integral part of these condensed consolidated financial statements. 1 Table of Contents ORCHESTRA BIOMED HOLDINGS, INC. Condensed Consolidated Statements of Operations and Comprehensive Loss (in thousands, except share and per share data) (Unaudited)